Get Adrenocortical Carcinoma: Basic Science and Clinical PDF

By David E. Schteingart (auth.), Gary D. Hammer, Tobias Else (eds.)

ISBN-10: 0387772359

ISBN-13: 9780387772356

ISBN-10: 0387772367

ISBN-13: 9780387772363

This first variation of the textbook “Adrenocortical Carcinoma: easy Sciences and medical options” offers a concise compilation of proper facts advancing our present realizing of this infrequent melanoma. Chapters are devoted to a variety of elements of either the elemental biology and the scientific technology in relation to adrenocortical carcinoma (ACC). specialist clinicians introduce the reader to present state of the art medical care of sufferers with ACC. As a substantial physique of information on ACC has collected over the past many years, specialist scientists have authored extra sections that function a reference resource for the skilled researcher in addition to an advent for the trainee within the laboratory or hospital. scientific themes span the epidemiology, prognosis and remedy of ACC. clinical subject matters components span the pathology and pathophysiology of ACC with a unique specialize in experimental types of adrenocortical tumors and up to date advances within the genetic points and signaling pathways in ACC. The content material of this e-book used to be compiled and edited with the motive of facilitating the interpretation of data into destiny diagnostic and healing instruments that might eventually increase sufferer care.

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Results of treatment with o,p -DDD in 138 patients. Am J Med 41:581–589 35. Lubitz JA et al (1973) Mitotane use in inoperable adrenal cortical carcinoma. JAMA 223:1109–1112 36. VanSlooten H et al (1984) The treatment of adrenocortical carcinoma with o,p -DDD: prognostic simplification of serum level monitoring. Eur J Cancer Oncol 20:47–53 37. Hogan TF et al (1978) o,p -DDD (mitotane) therapy of adrenal cortical carcinoma. Cancer 42:2177–2188 38. Lutton JP et al (1990) Clinical features of adrenocortical carcinoma, prognostic factors, and the effect of mitotane therapy.

Song JH et al (2008) The incidental adrenal mass on CT: prevalence of adrenal disease in 1,049 consecutive adrenal masses in patients with no known malignancy. AJR Am J Roentgenol 190(5):1163–1168 6. Terzolo M et al (1997) Prevalence of adrenal carcinoma among incidentally discovered adrenal masses. A retrospective study from 1989 to 1994. Gruppo Piemontese Incidentalomi Surrenalici. Arch Surg 132(8):914–919 7. National-Cancer-Institute (1975) Third national cancer survey: incidence data. DHEW Publ.

However, the authors have pointed out that pathological findings need to be combined with clinical information to achieve a proper FNA diagnosis. , surgery for limited disease vs. chemotherapy for metastatic disease) [46]. In this setting, adrenal biopsy, either as FNA cytology or as adrenal cut biopsy, will give a sensitivity and specificity of more than 80% and an overall accuracy of 90% [79]. Some researchers, however, are more enthusiastic concerning the use of image-guided FNA cytology for the characterization of adrenal masses.

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Adrenocortical Carcinoma: Basic Science and Clinical Concepts by David E. Schteingart (auth.), Gary D. Hammer, Tobias Else (eds.)


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